https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38917 2O₂ due to the isolation of the Au nanoparticles (AuNPs) from the PtNPs layer. Then the weak acidity of H₂O₂ can trigger the disassembly and reassembly of the AuNPs, resulting in the Janus distribution of large AuNPs aggregates. Such reconstruction of JMPA leads to the contact between PtNPs and AuNPs aggregates, thus changing the propulsion mechanism to self-electrophoresis. The asymmetric and aggregated AuNPs also enable the generation of a thermal gradient under laser irradiation, which propels the JMPA nanomotors by self-thermophoresis. Such multi-phoretic propulsion offers considerable promise for developing advanced nanomachines with a stimuli-responsive switch of propulsion modes in biomedical applications.]]> Wed 02 Mar 2022 15:43:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44959 Arx gene, critical to healthy neurodevelopment of PV interneurons, is reduced in the forebrain of MIA exposed mice. Finally, in a whole-genome sequenced patient cohort, we identified a novel missense mutation of ARX in a patient with schizophrenia and in the Psychiatric Genomics Consortium 2 cohort, a nominal association of proximal ARX SNPs with the disorder. This suggests MIA, as a risk factor for schizophrenia, may be influencing Arx expression to induce the GABAergic dysfunction seen in schizophrenia and that the ARX gene may play a role in the prenatal origins of schizophrenia pathophysiology.]]> Tue 25 Oct 2022 12:28:24 AEDT ]]>